Friday Seminar: Hélène FOHRER-TING & Sarah LEVESQUE
Hélène FOHRER-TING & Sarah LEVESQUE
Plateforme CHIC, Guido KROEMER's team
CRC UMRS1138
Open access FlowSOM-based toolbox
for efficient, exhaustive and semi-supervised
phenotyping of immune cell populations
Technological advances in cytometry are giving access to increasing qualitative and quantitative information at the single-cell level. Consequently, the large amount of data collected is rendering analysis an extremely complex, sub-optimal, and time-consuming task. To address this issue, several tools have been developed with the aim to automatize the visualization and interpretation of flow and mass cytometry data. One of these tools is FlowSOM, an R-based package that clusters cells according to their marker expression. We are building a novel package that applies FlowSOM clustering in a semi-supervised manner and offers extended visualizations of the cell clusters, together with integrated statistical evaluation. Overall, this novel tool releases unbiased, exhaustive, and efficient analysis of cytometry data.
Presentation by Sarah LEVESQUE
Invited by Maria-Chiara MAIURI & Jessica ZUCMAN-ROSSI
Friday December 13th 11h30
Gustave-Roussy Amphitheatre